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Quality products?make an important contribution to long-term revenue and profitability. Manufacturer supply high quality 2-Amino-5-methyl-3-thiophenecarbonitrile 138564-58-6 with GMP standards
1.What is the 2-Amino-5-methyl-3-thiophenecarbonitrile ?
An Impurity generated in the preparation of Olanzapine (O253750).
-
-
123-38-6
propionaldehyde
-
-
109-77-3
malononitrile
-
-
138564-58-6
2-amino-5-methylthiophene-3-carbonitrile
| Conditions | Yield |
|---|---|
|
With
sulfur; choline chloride; urea; sodium hydroxide;
In
water;
at 60 ℃;
for 2h;
Reagent/catalyst;
Temperature;
Green chemistry;
|
86%
|
|
With
sulfur;
In
neat (no solvent);
at 60 ℃;
for 2h;
|
79%
|
|
propionaldehyde;
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 1h;
malononitrile;
In
N,N-dimethyl-formamide;
at 20 ℃;
|
78%
|
|
propionaldehyde;
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 2.66667h;
malononitrile;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1.33333h;
Cooling with ice;
|
74%
|
|
propionaldehyde;
With
sulfur;
In
N,N-dimethyl-formamide;
at 0 - 20 ℃;
for 2h;
malononitrile;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 15h;
|
64%
|
|
propionaldehyde;
With
sulfur; triethylamine;
In
DMF (N,N-dimethyl-formamide);
at 0 - 18 ℃;
for 1.33333h;
malononitrile;
In
DMF (N,N-dimethyl-formamide);
at 18 ℃;
for 0.75h;
|
62.3%
|
|
With
zinc(II) oxide; sulfur;
In
ethanol;
at 85 ℃;
for 6h;
|
62%
|
|
propionaldehyde;
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
at 5 - 10 ℃;
for 1h;
malononitrile;
In
N,N-dimethyl-formamide;
at 18 - 20 ℃;
for 3h;
Further stages.;
|
60%
|
|
With
sulfur;
In
ethanol;
at 100 ℃;
for 2h;
|
52%
|
|
propionaldehyde;
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
at 18 ℃;
malononitrile;
In
N,N-dimethyl-formamide;
at 18 ℃;
for 1.83333h;
|
48%
|
|
With
1H-imidazole; sulfur;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 12h;
Inert atmosphere;
|
37%
|
|
With
sulfur;
In
ethanol;
for 4h;
Reflux;
Green chemistry;
|
20%
|
|
propionaldehyde;
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
for 1h;
Cooling with ice;
malononitrile;
In
N,N-dimethyl-formamide;
at 20 ℃;
|
7%
|
|
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
at 5 ℃;
for 0.75h;
|
|
|
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
|
-
-
123-38-6
propionaldehyde
-
-
4341-85-9
malonitrile
-
-
138564-58-6
2-amino-5-methylthiophene-3-carbonitrile
| Conditions | Yield |
|---|---|
|
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
at 5 ℃;
for 0.75h;
|
|
|
With
sulfur; triethylamine;
In
N,N-dimethyl-formamide;
at 0 - 5 ℃;
Inert atmosphere;
|
2.What is the CAS number for 2-Amino-5-methyl-3-thiophenecarbonitrile ?
The CAS number of 2-Amino-5-methyl-3-thiophenecarbonitrile is 138564-58-6.
More information of 2-Amino-5-methyl-3-thiophenecarbonitrile 138564-58-6 are:
|
CAS?Number |
138564-58-6 |
|
Density |
1.26 g/cm3 |
|
Melting Point |
101-103 °C |
|
Boiling Point |
318.5 °C at 760 mmHg |
|
Flash Point |
146.4 °C |
|
Refractive Index |
1.658 |
|
HS CODE |
29349990 |
|
PSA |
78.05000 |
|
LogP |
2.09158 |
|
Pka |
0.16±0.10(Predicted) |
3.What are another words for 2-Amino-5-methyl-3-thiophenecarbonitrile ?
Synonyms?for?2-Amino-5-methyl-3-thiophenecarbonitrile 138564-58-6:2-Amino-5-methyl-3-thiophenecarbonitrile;
4.What is the molecular formula of 2-Amino-5-methyl-3-thiophenecarbonitrile?
The chemical formula of ?2-Amino-5-methyl-3-thiophenecarbonitrile is?C6H6N2S which containing 6 Carbon atoms,6 Hydrogen atoms,2 Nitrogen atoms and 1 Sulfur atoms,and the molecular weight of??2-Amino-5-methyl-3-thiophenecarbonitrile?is 138.193.
5.What is 2-Amino-5-methyl-3-thiophenecarbonitrile (138564-58-6) used for?
InChI:InChI=1/C5H6N2O2S/c1-3-2-4(7(8)9)5(6)10-3/h2H,6H2,1H3
Relevant articles related to 2-Amino-5-methyl-3-thiophenecarbonitrile:
|
Article |
Source |
|
Ethylene diamine grafted nanoporous UiO-66 as an efficient basic catalyst in the multi-component synthesis of 2-aminithiophenes |
Erfaninia,Tayebee,Dusek,Amini , (2018) |
|
TiO2/nanoclinoptilolite as an efficient nanocatalyst in the synthesis of substituted 2-aminothiophenes |
Javadi, Farzad,Tayebee, Reza,Bahramian, Bahram , (2017) |
6.Buy 2-Amino-5-methyl-3-thiophenecarbonitrile with the best price .
Ningbo EST Chemical Co., Ltd is a quality supplier of 2-Amino-5-methyl-3-thiophenecarbonitrile. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on 2-Amino-5-methyl-3-thiophenecarbonitrile 138564-58-6.
