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Clozapine EP IMpurity D

  • CAS No.: 65514-71-8
  • Purity: 99%
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1.What is the Clozapine EP IMpurity D ?

Clozapine EP IMpurity D is used in the synthesis of substituted dibenzodiazepines. Also an impurity in the synthesis of Clozepine (C587500), an antipsychotic.

1-methyl-piperazine
109-01-3

1-methyl-piperazine

2-Iodobenzoic acid
88-67-5

2-Iodobenzoic acid

4-Chloro-2-nitroaniline
89-63-4

4-Chloro-2-nitroaniline

2-amino-4-chlorodiphenylamine-2'-carboxylic acid (4''-methyl)piperazide
65514-71-8

2-amino-4-chlorodiphenylamine-2'-carboxylic acid (4''-methyl)piperazide

Conditions
Conditions Yield
2-Iodobenzoic acid; 4-Chloro-2-nitroaniline; With copper(l) iodide; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 2h; Inert atmosphere;
1-methyl-piperazine; With oxalyl dichloride; triethylamine; In dichloromethane; at 0 ℃; for 1h;
With acetic acid; zinc; at 0 ℃; for 0.333333h;
87%
2-amino-4-chlorodiphenylamine-2'-carboxylic acid (4''-methyl)piperazide
65514-71-8

2-amino-4-chlorodiphenylamine-2'-carboxylic acid (4''-methyl)piperazide

clozaril
5786-21-0

clozaril

Conditions
Conditions Yield
2-amino-4-chlorodiphenylamine-2'-carboxylic acid (4''-methyl)piperazide; With N,N-dimethyl-aniline; trichlorophosphate; for 3h; Heating / reflux;
With ammonia; In water;
41%

2.What is the CAS number for Clozapine EP IMpurity D ?

The CAS number of Clozapine EP IMpurity D is 65514-71-8.

More information of Clozapine EP IMpurity D 65514-71-8 are:

CAS?Number

65514-71-8

Density

1.297g/cm3

Melting Point

>103°C (dec.)

Boiling Point

513.2oC at 760 mmHg

Flash Point

264.1oC

Vapor Pressure

1.21E-10mmHg at 25°C

Refractive Index

1.662

PSA

61.60000

LogP

3.58340

Pka

6.68±0.10(Predicted)

3.What are another words for Clozapine EP IMpurity D ?

Synonyms?for?Clozapine EP IMpurity D 65514-71-8:Piperazine,1-[2-[(2-amino-4-chlorophenyl)amino]benzoyl]-4-methyl;

4.What is the molecular formula of Clozapine EP IMpurity D?

The chemical formula of ?Clozapine EP IMpurity D is?C18H21ClN4O which containing 18 Carbon atoms,21 Hydrogen atoms,1 Chlorine atoms,4 Nitrogen atoms and 1 Oxygen atoms,and the molecular weight of??Clozapine EP IMpurity D?is 344.844.

5.What is Clozapine EP IMpurity D (65514-71-8) used for?

Clozapine EP IMpurity D is a chemical compound that serves as an impurity in the synthesis of Clozapine, an antipsychotic medication. It is also used in the synthesis of substituted dibenzodiazepines, a class of compounds with potential therapeutic applications.

InChI:InChI=1/C18H21ClN4O/c1-22-8-10-23(11-9-22)18(24)14-4-2-3-5-16(14)21-17-7-6-13(19)12-15(17)20/h2-7,12,21H,8-11,20H2,1H3

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