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1.What is the Coproporphyrinogen III ?
Used in Medical Research:
Coproporphyrinogen III is used as a research subject for understanding the heme biosynthetic pathway and its role in the formation of hemoglobin and other heme-containing proteins. Studying its functions and metabolism is crucial for the development of treatments for porphyria and other heme-related disorders.
Used in Pharmaceutical Development:
Coproporphyrinogen III is used as a target for the development of drugs and therapies to treat porphyria diseases and other conditions related to heme metabolism abnormalities. By modulating the activity of enzymes involved in the biosynthetic pathway, it may be possible to alleviate symptoms and improve patient outcomes.
Used in Diagnostics:
Coproporphyrinogen III can be used as a biomarker for the diagnosis of porphyria diseases and other heme metabolism disorders. Measuring the levels of coproporphyrinogen III in biological samples can help identify abnormalities in the heme biosynthetic pathway and guide appropriate treatment strategies.
Used in Biochemical Education:
Coproporphyrinogen III serves as an educational tool for teaching students about the complex process of heme biosynthesis and its importance in various biological functions. Understanding the role of coproporphyrinogen III in this pathway can help students appreciate the intricacies of metabolic pathways and their relevance to human health.
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![3-{5-Formyl-2-[5-formyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-ylmethyl]-4-methyl-1H-pyrrol-3-yl}-propionic acid methyl ester](/upload/2026/8/1da24f1513f940b7a9f45a7b7a1ffdfe_c9100f7d-5afb-44f5-9f14-ea5eb9ff72bb.png)
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4792-10-3
3-{5-Formyl-2-[5-formyl-3-(2-methoxycarbonyl-ethyl)-4-methyl-1H-pyrrol-2-ylmethyl]-4-methyl-1H-pyrrol-3-yl}-propionic acid methyl ester
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2624-63-7
coproporphyrinogen III
| Conditions | Yield |
|---|---|
|
Multi-step reaction
with
2
steps
1: 58 percent / 1.) trifluoroacetic acid, 2.) sodium acetate / methanol; CH2
Cl2
/ 1.) 2-3 deg C 90 min, 2.) 18 deg C 5 min, 3.) 50 min
2: 1.) 2M aq. potassium hydroxide; 2.) sodium amalgam / 1.) tetrahydrofuran 20 deg C; 2.) 3-4 min
With
potassium hydroxide; sodium amalgam; sodium acetate; trifluoroacetic acid;
In
methanol; dichloromethane;
|
|
|
Multi-step reaction
with
5
steps
1: 68 percent / sodium / 0.3 h / 18 °C
2: 41 percent / 1.) trifluoroacetic acid / methanol; CH2
Cl2
/ 1.) 2-3 deg C 70 min, 2.) 18 deg C 2 min, 20 min
3: 100 percent / H2
/ 10percent palladized charcoal / acetic acid / 4 h / Ambient temperature
4: sodium amalgam, aq. acetic acid / 18 h / 37 °C / enzymes from Euglena gracilis
5: 1.) 2M aq. potassium hydroxide; 2.) sodium amalgam / 1.) tetrahydrofuran 20 deg C; 2.) 3-4 min
With
potassium hydroxide; sodium amalgam; hydrogen; sodium; acetic acid; trifluoroacetic acid;
palladium on activated charcoal;
In
methanol; dichloromethane; acetic acid;
|
|
|
Multi-step reaction
with
5
steps
1: 68 percent / sodium / 0.3 h / 18 °C
2: 40 percent / trifluoroacetic acid / 2-3 deg C 70 min, CH2
Cl2
-CH3
OH 18 deg C 2 min
3: 95 percent / H2
/ 10percent palladized charcoal / acetic acid / 4 h / Ambient temperature
4: sodium amalgam, aq. acetic acid / 18 h / 37 °C / enzymes from Euglena gracilis
5: 1.) 2M aq. potassium hydroxide; 2.) sodium amalgam / 1.) tetrahydrofuran 20 deg C; 2.) 3-4 min
With
potassium hydroxide; sodium amalgam; hydrogen; sodium; acetic acid; trifluoroacetic acid;
palladium on activated charcoal;
In
acetic acid;
|
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111980-20-2
heptaprophyrinogen III
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2624-63-7
coproporphyrinogen III
| Conditions | Yield |
|---|---|
|
heptaprophyrinogen III;
With
ethylenediaminetetraacetic acid; DL-dithiothreitol;
uroporphyrinogen decarboxylase;
In
phosphate buffer; water;
at 37 ℃;
pH=6.8;
With
ethylenediaminetetraacetic acid; DL-dithiothreitol;
uroporphyrinogen decarboxylase;
In
phosphate buffer; water;
at 37 ℃;
With
ethylenediaminetetraacetic acid; DL-dithiothreitol;
uroporphyrinogen decarboxylase;
In
phosphate buffer; water;
at 37 ℃;
Further stages.;
|
2.What is the CAS number for Coproporphyrinogen III ?
The CAS number of Coproporphyrinogen III is 2624-63-7.
More information of Coproporphyrinogen III 2624-63-7 are:
|
CAS?Number |
2624-63-7 |
|
Density |
1.358g/cm3 |
|
Boiling Point |
961°Cat760mmHg |
|
Flash Point |
535°C |
|
PSA |
212.36000 |
|
LogP |
4.97800 |
|
Pka |
4.70±0.10(Predicted) |
3.What are another words for Coproporphyrinogen III ?
Synonyms?for?Coproporphyrinogen III 2624-63-7:2,7,12,18-Porphinetetrapropionicacid, 5,10,15,20,22,24-hexahydro-3,8,13,17-tetramethyl- (8CI); CoproporphyrinIII, hexahydro deriv. (6CI); Coproporphyrinogen III (7CI)
4.What is the molecular formula of Coproporphyrinogen III?
The chemical formula of ?Coproporphyrinogen III is?C36H44 N4 O8 which containing 36 Carbon atoms,44 Hydrogen atoms,4 Nitrogen atoms and 8 Oxygen atoms,and the molecular weight of??Coproporphyrinogen III?is 660.767.
5.What is Coproporphyrinogen III (2624-63-7) used for?
Coproporphyrinogen III is a vital chemical compound involved in the heme biosynthetic pathway, essential for the formation of hemoglobin and other heme-containing proteins. It serves as a substrate for the enzyme coproporphyrinogen oxidase, which catalyzes the formation of protoporphyrinogen IX, another key intermediate in the heme biosynthesis process. Coproporphyrinogen III is also implicated in certain porphyria diseases, which are disorders characterized by abnormalities in heme metabolism.
Relevant articles related to Coproporphyrinogen III:
|
Article |
Source |
|
Revisiting the Mechanism of the Anaerobic Coproporphyrinogen III Oxidase HemN |
Ji, Xinjian,Mo, Tianlu,Liu, Wan-Qiu,Ding, Wei,Deng, Zixin,Zhang, Qi , p. 6235 - 6238 (2019) |
|
The oxygen-independent coproporphyrinogen III oxidase HemN utilizes harderoporphyrinogen as a reaction intermediate during conversion of coproporphyrinogen III to protoporphyrinogen IX |
Rand, Katrin,Noll, Claudia,Schiebel, Hans Martin,Kemken, Dorit,Duelcks, Thomas,Kalesse, Markus,Heinz, Dirk W.,Layer, Gunhild experimental part, p. 55 - 63 (2011/11/05) |
6.Buy Coproporphyrinogen III with the best price .
Ningbo EST Chemical Co., Ltd is a quality supplier of Coproporphyrinogen III. Our main goal is customer satisfaction. Contact us to negotiate the best price for your business on Coproporphyrinogen III 2624-63-7.
